Department of Anatomy, Inje University
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Kim Hye Young


김혜영 (Kim Hye Young) 조교수 Assistant Professor
이학박사 (PhD.)

2023년 인제의대 발령

♦ 강의분야 : 해부학, 조직학, 발생학
♦ 연구분야 : 대사성질환, POPs에 의한 환경질환, 시스템생물학

 

[연구논문]

  1. Environ Toxicol. 2022 Sep;37(9):2223-2234. Hepatic STAMP2 alleviates polychlorinated biphenyl-induced steatosis and hepatic iron overload in NAFLD models. Hye Young Kim, Chul Hee Park, Joon Beom Park, Kangeun Ko, Mi Hwa Lee, Jin Chung , Young Hyun Yoo
  2. Biomedicines 2022 Aug 26;10(9):2082. The Role of STAMP2 in Pathogenesis of Chronic Diseases Focusing on Nonalcoholic Fatty Liver Disease: A Review. Hye Young Kim, Young Hyun Yoo
  3. Kosin Medical Journal 2022 Sep;37(3):213-219. Effectiveness of prophylactic calcium and vitamin D supplementation for preventing post-thyroidectomy hypocalcemia: a meta-analysis. Hyeyeon Moon, Ju Won Seok, Keunyoung Kim, Hye Young Kim, Mi Kyoung Park, In Joo Kim, Kyoungjune Pak*, Sunghwan Suh*
  4. Int J Mol Sci. 2022 Aug 10;23(16):8899. Recombinant FGF21 Attenuates Polychlorinated Biphenyl-Induced NAFLD/NASH by Modulating Hepatic Lipocalin-2 Expression. Hye Young Kim, Young Hyun Yoo
  5. J Toxicol Sci. 2022;47(8):317-326. Constitutive expression of cytochrome P450 1B1 endows testicular Leydig cells with susceptibility to 7,12-dimethylbenzanthracene-induced cell death. Yoon-Jae Kim, Ji-Eun Park, Jin-Yong Chung, Ji Young Kim, Seung Gee Lee, Seung-Jin Lee, Wook-Joon Yu, Hye Young Kim, Hyeon Jun Kim, Hyungjong Koh, Hae-Rahn Bae, Young Hyun Yoo, Jong-Min Kim
  6. Biotechnology and Bioprocess Engineering 2022;27(3):386–397. The Inhibitory Effect of Corni Fructus against Oxidative Stress-induced Cellular Damage in C2C12 Murine Myoblasts. Sung Ok Kim, Ji-Suk Jeung, Cheol Park, Hyesook Lee, Sung Hyun Choi, Gi-Young Kim, Hye Young Kim, Yung Hyun Choi & Eunjoo H. Lee
  7. FASEB J. 2020 Sep;34(9):12354-12366. Hepatic STAMP2 mediates recombinant FGF21-induced improvement of hepatic iron overload in nonalcoholic fatty liver disease. Hye Young Kim, Woo Young Kwon, Joon Beom Park, Mi Hwa Lee, Yoo Jin Oh, SungHwan Suh, Yang Hyun Baek, Jin Sook Jeong, Young Hyun Yoo.
  8. Dev Reprod. 2020 Sep;24(3):231-239. Hepatic Steatosis Alleviated in Diabetic Mice upon Dietary Exposure to Fibroin via Transgenic Rice: Potential STAMP2 Involvement in Hepatocytes. Ji-Eun Park, Yeon Jae Jeong, Hye Young Kim, Young Hyun Yoo, Kwang Sik Lee, Won Tae Yang, Doh Hoon Kim, Jong-Min Kim.
  9. Dev Reprod. 2019 Sep;23(3):223-229. Dietary Exposure to Transgenic Rice Expressing the Spider Silk Protein Fibroin Reduces Blood Glucose Levels in Diabetic Mice: The Potential Role of Insulin Receptor Substrate-1 Phosphorylation in Adipocytes. Ji-Eun Park, Yeon Jae Jeong, Joon Beom Park, Hye Young Kim, Young Hyun Yoo, Kwang Sik Lee, Won Tae Yang, Doh Hoon Kim, Jong-Min Kim.
  10. Int J Environ Res Public Health. 2019 Feb 3;16(3). Persistent Organic Pollutant-Mediated Insulin Resistance. Kim YA, Park JB, Woo MS, Lee SY, Kim HY, Yoo YH.
  11. Mol Pharmacol. 2018 Dec;94(6):1401-1411. Cilostazol Improves HFD-Induced Hepatic Steatosis by Upregulating Hepatic STAMP2 Expression through AMPK. Oh YJ, Kim HY (공동1저자), Lee MH, Suh SH, Choi Y, Nam TG, Kwon WY, Lee SY, Yoo YH.
  12. Biochem Biophys Res Commun. 2018 Sep 10;503(3):1260-1266. Palmitate induces lipoapoptosis in Schwann cells through ROS generation-mediated STAMP2 downregulation. Lee SW, Park JB, Kim HJ, Kim HY, Lee SY, Chung WT, Shin YK, Park HT, Rho JH, Yoo YH.
  13. Toxicol Lett. 2018 Aug;292:55-62. Polychlorinated biphenyl 138 exposure-mediated lipid droplet enlargement endows adipocytes with resistance to TNF-α-induced cell death. Kim YA, KimHY, Oh YJ, Kwon WY, Lee MH, Bae JY, Woo MS, Kim JM, Yoo YH.
  14. Bone Res. 2018 Jul 6;6:20. Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27. Lee SW, Rho JH, Lee SY, Chung WT, Oh YJ, Kim JH, Yoo SH, Kwon WY, Bae JY, Seo SY, Sun H, KimHY, Yoo YH.
  15. Arch Toxicol. 2017 Jun;91(6):2353-2363. Polychlorinated biphenyls exposure-induced insulin resistance is mediated by lipid droplet enlargement through Fsp27. Kim HY, Kwon WY, Kim YA, Oh YJ, Yoo SH, Lee MH, Bae JY, Kim JM, Yoo YH.
  16. Journal of Hepatology 2015 Aug;63(2):477-85. Hepatic STAMP2 alleviates high fat diet-induced hepatic steatosis and insulin resistance. Kim HY, Park SY, Lee MH, Rho JH, Oh YJ, Jung HU, Yoo SH, Jeong NY, Lee HJ, Suh S, Seo SY, Cheong J, Jeong JS, Yoo YH.
  17. Osteoarthritis Cartilage 2015 Dec;23(12):2269-78. Leptin protects rat articular chondrocytes from cytotoxicity induced by TNF-α in the presence of cyclohexamide. Lee SW, Rho JH, Lee SY, Kim JH, Cheong JH, KimHY, Jeong NY, Chung WT, Yoo YH.
  18. Cancer Lett. 2014 Dec 1;355(1):61-9. Sorafenib overcomes the chemoresistance in HBx-expressing hepatocellular carcinoma cells through down-regulation of HBx protein stability and suppresses HBV gene expression. Kim HY, Jung HU, Yoo SH, Yoo KS, Cheong J, Park BS, Yun I, Yoo YH.
  19. Cell Death Dis. 2014 Jun 26;5:e1303. Retinal pigment epithelial cells undergoing mitotic catastrophe are vulnerable to autophagy inhibition. Lee SY, Oh JS, Rho JH, Jeong NY, Kwon YH, Jeong WJ, Ryu WY, Ahn HB, Park WC, Rho SH, Yoon YG, Jeong SY, Choi YH, Kim HY, Yoo YH.
  20. Int J Biol Sci. 2014 Mar 8;10(3):321-6. STAMPing into Mitochondria. Yoo SK, Cheong J, Kim HY.
  21. World J Gastroenterol. 2014 Jan 7;20(1):175-82. Bile acid increases expression of the histamine-producing enzyme, histidine decarboxylase, in gastric cells. Ku HJ, Kim HY, Kim HH, Park HJ, Cheong JH.
  22. Toxicol Appl Pharmacol. 2013 Jan 1;266(1):9-18. The targeted inhibition of mitochondrial Hsp90 overcomes the apoptosis resistance conferred by Bcl-2 in Hep3Bcells vi a necroptosis. Yan C, Oh JS, Yoo SH, Lee JS, Yoon YG, Oh YJ, Jang MS, Lee SY, Yang J, Lee SH, Kim HY, Yoo YH.
  23. Neuro Oncol. 2012 Nov;14(11):1332-45. Expression of αB-crystallin overrides the anti-apoptotic activity of XIAP. Lee JS, Kim HY (공동1저자), Jeong NY, Lee SY, Yoon YG, Choi YH, Yan C, Chu IS, Koh H, Park HT, Yoo YH.
  24. Exp Mol Med. 2012 Oct 31;44(10):622-32. Hepatic STAMP2 decreases hepatitis B virus X protein-associated metabolic deregulation. Kim HY, Cho HK, Yoo SK, Cheong JH.
  25. Gen Comp Endocrinol. 2012 Jan 1;175(1):39-47. Characterization of Paralichthys olivaceus peroxisome proliferator- activated receptor-α gene as a master regulator of flounder lipid metabolism. Cho HK, Kong HJ, Kim HY, Cheong J.
  26. Cancer Lett. 2011 Oct 28;309(2):176-84. Hepatitis B virus X protein stimulates the Hedgehog-Gli activation through protein stabilization and nuclear localization of Gli1 in liver cancer cells. Kim HY, Cho HK, Hong SP, Cheong J.
  27. Mol Hum Reprod. 2011 Nov;17(11):710-9. Hypoxia induces expression of COX-2 through the homeodomain transcription factor CDX1 and orphan nuclear receptor SHP in human endometrial cells. Kim KH, Kim HY, Kim HH, Lee KS, Cheong J.
  28. Virus Res. 2011 Jun;158(1-2):55-61. Oxygenated derivatives of cholesterol promote hepatitis B virus gene expression through nuclear receptor LXRα activation. Kim HY, Cho HK, Kim HH, Cheong J.
  29. Biochem J. 2011 Apr 15;435(2):431-9. Endoplasmic Reticulum stress induced by Hepatitis B virus X protein enhances cyclooxygenase 2 expression via activating transcription factor-4. Cho HK, Cheong KJ, Kim HY, Cheong J.
  30. FEBS J. 2010 Jul;277(13):2791-802. Bile acids increase hepatitis B virus gene expression and inhibit interferon-alpha activity. Kim HY, Cho HK, Choi YH, Lee KS, Cheong J.
  31. Carcinogenesis. 2010 Apr;31(4):679-86. The SDF-1alpha/CXCR4 axis induces the expression of fatty acid synthase via sterol regulatory element-binding protein-1 activation in cancer cells. Kim K, Kim HY, Cho HK, Kim KH, Cheong J.
  32. Biochem J. 2010 Apr 14;427(3):413-22. The small heterodimer partner suppresses the transcriptional activity and nuclear localization of Hedgehog signalling protein Gli1. Kim K, Kim KH, Cho HK, Kim HY, Kim HH, Cheong J.
  33. FEBS Lett. 2010 Feb 19;584(4):707-712. Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway. Kim K, Kim KH, Kim HY, Cho HK, Sakamoto N, Cheong J.
  34. Cell Signal. 2009 Aug;21(8):1269-76. Oleic acid inhibits hepatic insulin signaling through deregulation of STAT3 activation and C/EBPalpha expression. Kim K, Kim HY, Son EJ, Heo J, Cheong J.
  35. FEBS Lett. 2009 Jan 5;583(1):29-35. Homeodomain transcription factor CDX1 is required for the transcriptional induction of PPARgamma in intestinal cell differentiation. Park MJ, Kim HY, Kim K, Cheong J.
  36. Carcinogenesis. 2008 Dec;29(12):2385-93. Bile acid induces expression of COX-2 through the homeodomain transcription factor CDX1 and orphan nuclear receptor SHP in human gastric cancer cells. Park MJ, Kim KH, Kim HY, Kim K, Cheong J.
  37. Biochem Biophys Res Commun. 2008 May 2;369(2):437-43. Bile acid regulates c-Jun expression through the orphan nuclear receptor SHP induction in gastric cells.Park WI, Park MJ, An JK, Choi YH, Kim HY, Cheong J, Yang US.
  38. Exp Cell Res. 2007 May 15;313(9):1866-76. HIF-1alpha expression in response to lipopolysaccaride mediates induction of hepatic inflammatory cytokine TNFalpha. Kim HY, Kim YH, Nam BH, Kong HJ, Kim HH, Kim YJ, An WG, Cheong J.
  39. Biochem J. 2007 Mar 15;402(3):567-74. Transcriptional repression of the gluconeogenic gene PEPCK by the orphan nuclear receptor SHP through inhibitory interaction with C/EBPalpha. Park MJ, Kong HJ, Kim HY, Kim HH, Kim JH, Cheong JH.