Hur Dae Young
허대영 (Hur Dae Young) 교수 Professor
의학박사 (MD., PhD.)
2000년 인제의대 발령
♦ 강의분야 : 해부학, 조직학, 발생학, 신경해부학, 법의학
♦ 연구분야 : Epstein Barr virus 관련질환, 종양특이항원, 세포사멸
[연구논문]
- Endogenous interleukin-18 modulates immune escape of murine melanoma cells by regulating the expression of Fas ligand and reactive oxygen intermediates. Cho D, Song H, Kim YM, Houh D, Hur DY, Park H, Yoon D, Pyun KH, Lee WJ, Kurimoto M, Kim YB, Kim YS, Choi I. Cancer Res. 2000 May 15;60(10):2703-9.
- Role of follicular dendritic cells in the apoptosis of germinal center B cells. Hur DY, Kim DJ, Kim S, Kim YI, Cho D, Lee DS, Hwang Y, Bae K, Chang KY, Lee WJ. Immunol Lett. 2000 May 1;72(2):107-11.
- CM1, a possible novel activation molecule on human lymphocytes. Hur DY, Kim S, Kim YI, Min HY, Kim DJ, Lee DS, Cho D, Hwang YI, Hwang DH, Park SH, Ahn HK, Chang KY, Kim YB, Lee WJ. Immunol Lett. 2000 Oct 3;74(2):95-102.
- CM1 ligation initiates apoptosis in a caspase 8-dependent manner in Ramos cells and in a mitochondria-controlled manner in Raji cells. Kim D, Hur DY, Kim YS, Lee K, Lee Y, Cho D, Kang JS, Kim YI, Hahm E, Yang Y, Yoon S, Kim S, Lee WB, Park HY, Kim YB, Hwang YI, Chang KY, Lee WJ. Hum Immunol. 2002 Jul;63(7):576-87.
- Vitamin D(3) up-regulating protein 1 (VDUP1) antisense DNA regulates tumorigenicity and melanogenesis of murine melanoma cells via regulating the expression of fas ligand and reactive oxygen species. Song H, Cho D, Jeon JH, Han SH, Hur DY, Kim YS, Choi I. Immunol Lett. 2003 May 1;86(3):235-47.
- L-ascorbic acid (vitamin C) induces the apoptosis of B16 murine melanoma cells via a caspase-8-independent pathway. Kang JS, Cho D, Kim YI, Hahm E, Yang Y, Kim D, Hur D, Park H, Bang S, Hwang YI, Lee WJ. Cancer Immunol Immunother. 2003 Nov;52(11):693-8. Epub 2003 Jun 24.
- Vitamin C downregulates interleukin-18 production by increasing reactive oxygen intermediate and mitogen-activated protein kinase signalling in B16F10 murine melanoma cells. Cho D, Hahm E, Kang JS, Kim YI, Yang Y, Park JH, Kim D, Kim S, Kim YS, Hur D, Park H, Pang S, Hwang YI, Lee WJ. Melanoma Res. 2003 Dec;13(6):549-54.
- Resistance to cytotoxic chemotherapy is induced by NK cells in non-Hodgkin’s Lymphoma Cells. Cho D, Kim YI, Kang JS, Hahm E, Yang Y, Kim D, Kim S, Kim YS, Hur D, Park H, Hwang YI, Kim TS, Lee WJ. J Clin Immunol. 2004 Sep;24(5):553-60.
- Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells via the down-regulation of transferrin receptor dependent iron uptake. Kang JS, Cho D, Kim YI, Hahm E, Kim YS, Jin SN, Kim HN, Kim D, Hur D, Park H, Hwang YI, Lee WJ. J Cell Physiol. 2005 Jul;204(1):192-7.
- CD19 signalling improves the Epstein-Barr virus-induced immortalization of human B cell. Hur DY, Lee MH, Kim JW, Kim JH, Shin YK, Rho JK, Kwack KB, Lee WJ, Han BG. Cell Prolif. 2005 Feb;38(1):35-45.
- TGF-beta inhibits Fas-mediated apoptosis of a follicular dendritic cell line by down-regulating the expression of Fas and caspase-8: counteracting role of TGF-beta on TNF sensitization of Fas-mediated apoptosis. Park SM, Kim S, Choi JS, Hur DY, Lee WJ, Lee MS, Choe J, Lee TH. J Immunol. 2005 May 15;174(10):6169-75.
- Interleukin-18 is a critical factor for vascular endothelial growth factor-enhanced migration in human gastric cancer cell lines. Kim KE, Song H, Kim TS, Yoon D, Kim CW, Bang SI, Hur DY, Park H, Cho DH. Oncogene. 2007 Mar 1;26(10):1468-76. Epub 2006 Sep 25.
- IL-18 enhances the migration ability of murine melanoma cells through the generation of ROI and the MAPK pathway. Jung MK, Song HK, Kim KE, Hur DY, Kim T, Bang S, Park H, Cho DH. Immunol Lett. 2006 Nov 15;107(2):125-30. Epub 2006 Sep 11.
- Ligation of centrocyte/centroblast marker 1 on Epstein-Barr virus–transformed B lymphocytes induces cell death in a reactive oxygen species–dependent manner. Kim YS, Park GB, Choi YM, Kwon OS, Song HK, Kang JS, Kim YI, Lee WJ, Hur DY. Hum Immunol. 2006 Oct;67(10):795-807. Epub 2006 Aug 11.
- IL-2/IL-18 prevent the down-modulation of NKG2D by TGF-beta in NK cells via the c-Jun N-terminal kinase (JNK) pathway. Song H, Hur DY, Kim KE, Park H, Kim T, Kim CW, Bang S, Cho DH. Cell Immunol. 2006 Jul;242(1):39-45. Epub 2006 Oct 27.
- The molecular mechanisms of vitamin C on cell cycle regulation in B16F10 murine melanoma. Hahm E, Jin DH, Kang JS, Kim YI, Hong SW, Lee SK, Kim HN, Jung da J, Kim JE, Shin DH, Hwang YI, Kim YS, Hur DY, Yang Y, Cho D, Lee MS, Lee WJ. J Cell Biochem. 2007 Nov 1;102(4):1002-10.
- Cross-linking of CD54 on Burkitt lymphoma cell line Raji and Ramos induces FasL expression by reactive oxygen species and apoptosis of adjacent cells in Fas/FasL interaction. Kim YS, Park GB, Song HK, Hur I, Lee HK, Kang JS, Hahm E, Lee WJ, Hur DY. J Immunother. 2007 Oct;30(7):727-39.
- Vitamin C suppresses proliferation of the human melanoma cell SK-MEL-2 through the inhibition of cyclooxygenase-2 (COX-2) expression and the modulation of insulin-like growth factor II (IGF-II) production. Lee SK, Kang JS, Jung da J, Hur DY, Kim JE, Hahm E, Bae S, Kim HW, Kim D, Cho BJ, Cho D, Shin DH, Hwang YI, Lee WJ. J Cell Physiol. 2008 Jul;216(1):180-8.
- B7-H4 reverse signaling induces the apoptosis of EBV-transformed B cells through Fas ligand up-regulation. Song H, Park G, Kim YS, Hur I, Kim H, Ryu JW, Lee HK, Cho DH, Choi IH, Lee WJ, Hur DY. Cancer Lett. 2008 Aug 8;266(2):227-37. Epub 2008 Apr 15.
- IL-18 enhances ULBP2 expression through the MAPK pathway in leukemia cells. Song H, Kim KE, Hur D, Lim JS, Yang Y, Cho BJ, Kim CH, Kim T, Bang S, Lee WJ, Park H, Cho D. Immunol Lett. 2008 Oct 30;120(1-2):103-7. Epub 2008 Aug 13.
- Secondary apoptosis of spiral ganglion cells induced by aminoglycoside: Fas-Fas ligand signaling pathway. Bae WY, Kim LS, Hur DY, Jeong SW, Kim JR. Laryngoscope. 2008 Sep;118(9):1659-68.
- Cross-linking of B7-H1 on EBV-transformed B cells induces apoptosis through reactive oxygen species production, JNK signaling activation, and fasL expression. Kim YS, Park GB, Lee HK, Song H, Choi IH, Lee WJ, Hur DY. J Immunol. 2008 Nov 1;181(9):6158-69.
- Expression of ADAM33 is a novel regulatory mechanism in IL-18-secreted process in gastric cancer. Kim KE, Song H, Hahm C, Yoon SY, Park S, Lee HR, Hur DY, Kim T, Kim CH, Bang SI, Bang JW, Park H, Cho DH. J Immunol. 2009 Mar 15;182(6):3548-55.
- Interleukin-18 induces transferrin expression in breast cancer cell line MCF-7. Park S, Yoon SY, Kim KE, Lee HR, Hur DY, Song H, Kim D, Bang SI, Cho DH. Cancer Lett. 2009 Dec 28;286(2):189-95. Epub 2009 Jun 16.
- Doxorubicin enhances CD4(+) T-cell immune responses by inducing expression of CD40 ligand and 4-1BB. Park JY, Jang MJ, Chung YH, Kim KY, Kim SS, Lee WB, You S, Choi YS, Hur DY, Kim D. Int Immunopharmacol. 2009 Dec;9(13-14):1530-9. Epub 2009 Sep 22.
- Role of acidic mammalian chitinase and chitotriosidase in nasal polyps. Park SK, Cho HW, Heo KW, Hur DY, Lee HK. Otolaryngol Head Neck Surg. 2009 Oct;141(4):462-6.
- Enalapril alters expression of key growth factors in experimental diabetic retinopathy. Kim HW, Kim JL, Lee HK, Hur DY, Yun IH, Kim SD. Curr Eye Res. 2009 Nov;34(11):976-87.
- Cell cycle arrest induced by engagement of B7-H4 on Epstein-Barr virus-positive B-cell lymphoma cell lines. Park GB, Song H, Kim YS, Sung M, Ryu JW, Lee HK, Cho DH, Kim D, Lee WJ, Hur DY. Immunology. 2009 Nov;128(3):360-8.
- Serum levels of IL-18 and sIL-2R in patients with alopecia areata receiving combined therapy with oral cyclosporine and steroids. Lee D, Hong SK, Park SW, Hur DY, Shon JH, Shin JG, Hwang SW, Sung HS. Exp Dermatol. 2010 Feb;19(2):145-7. Epub 2009 Sep 15.
- Tannic acid and quercetin display a therapeutic effect in atopic dermatitis via suppression of angiogenesis and TARC expression in Nc/Nga mice. Jung MK, Hur DY, Song SB, Park Y, Kim TS, Bang SI, Kim S, Song HK, Park H, Cho DH. J Invest Dermatol. 2010 May;130(5):1459-63. Epub 2010 Jan 7.
- Gentamicin-induced spiral ganglion cell death: apoptosis mediated by ROS and the JNK signaling pathway. Jeong SW, Kim LS, Hur D, Bae WY, Kim JR, Lee JH. Acta Otolaryngol. 2010 Jun;130(6):670-8.
- Simvastatin suppresses expression of angiogenic factors in the retinas of rats with streptozotocin-induced diabetes. Lee SG, Kim JL, Lee HK, Ryu GW, Hur DY, Yun IH, Yang JW, Kim HW. Graefes Arch Clin Exp Ophthalmol. 2011 Mar;249(3):389-97. Epub 2010 Sep 7.
- Endoplasmic reticulum stress-mediated apoptosis of EBV-transformed B cells by cross-linking of CD70 is dependent upon generation of reactive oxygen species and activation of p38 MAPK and JNK pathway. Park GB, Kim YS, Lee HK, Song H, Cho DH, Lee WJ, Hur DY. J Immunol. 2010 Dec 15;185(12):7274-84. Epub 2010 Nov 15.
- IDO metabolite produced by EBV-transformed B cells inhibits surface expression of NKG2D in NK cells via the c-Jun N-terminal kinase (JNK) pathway.Song H, Park H, Kim J, Park G, Kim YS, Kim SM, Kim D, Seo SK, Lee HK, Cho D, Hur D. Immunol Lett. 2011 May;136(2):187-93. Epub 2011 Jan 26.
- L-kynurenine-induced apoptosis in human NK cells is mediated by reactive oxygen species. Song H, Park H, Kim YS, Kim KD, Lee HK, Cho DH, Yang JW, Hur DY. Int Immunopharmacol. 2011 Aug;11(8):932-8. Epub 2011 Feb 23.
- Changes in murine hair with dietary selenium excess or deficiency. Hwang SW, Lee HJ, Suh KS, Kim ST, Park SW, Hur DY, Lee D, Seo JK, Sung HS. Exp Dermatol. 2011 Apr;20(4):367-9. Epub 2011 Mar 1.
- Expression of chitinases in hypertrophied adenoids of children. Heo KW, Hur DY, Park SK, Yang YI, Kwak HH, Kim TY. Otolaryngol Head Neck Surg. 2011 Oct;145(4):660-5. Epub 2011 May 25.
- Chitinolytic activity in nasal polyps. Park SK, Heo KW, Hur DY, Yang YI. Am J Rhinol Allergy. 2011 Jan-Feb;25(1):12-4.
- Interleukin-18-mediated interferon-gamma secretion is regulated by thymosin beta 4 in human NK cells. Lee HR, Yoon SY, Song SB, Park Y, Kim TS, Kim S, Hur DY, Song HK, Park H, Cho D. Immunobiology. 2011 Oct;216(10):1155-62. Epub 2011 Apr 13.
- 1,25-Dihydroxyvitamin D₃ enhances NK susceptibility of human melanoma cells via Hsp60-mediated FAS expression. Lee JH, Park S, Cheon S, Lee JH, Kim S, Hur DY, Kim TS, Yoon SR, Yang Y, Bang SI, Park H, Lee HT, Cho D. Eur J Immunol. 2011 Oct;41(10):2937-46. Epub 2011 Sep 6.
- Effects of methotrexate on vascular endothelial growth factor, angiopoietin 1, and angiopoietin 2 in nasal polyps. Park SK, Kim HI, Yang YI, Hur DY. Am J Rhinol Allergy. 2011 Jul-Aug;25(4):e129-32.
- Effect of lipoic acid on expression of angiogenic factors in diabetic rat retina. Lee SG, Lee CG, Yun IH, Hur DY, Yang JW, Kim HW. Clin Experiment Ophthalmol. 2012 Jan-Feb;40(1):e47-57. Epub 2011 Nov 4.
- Selenium inhibits migration of murine melanoma cells via down-modulation of IL-18 expression. Song H, Kim J, Lee HK, Park HJ, Nam J, Park GB, Kim YS, Cho D, Hur DY. Int Immunopharmacol. 2011 Dec;11(12):2208-13. Epub 2011 Oct 18.
- Reactive oxygen species and p38 MAPK regulate Bax translocation and calcium redistribution in salubrinal-induced apoptosis of EBV-transformed B cells. Park GB, Kim YS, Lee HK, Song H, Kim S, Cho DH, Hur DY. Cancer Lett. 2011 Dec 27;313(2):235-48. Epub 2011 Sep 17.
- CD40 stimulation induces vincristine resistance via AKT activation and MRP1 expression in a human multiple myeloma cell line. Lee SW, Cho HY, Na G, Yoo MR, Seo SK, Hur DY, Han J, Lee CK, Choi I. Immunol Lett. 2012 May 30;144(1-2):41-8.
- Effects of dexamethasone or methotrexate on chitinolytic activity in nasal polyps. Park SK, Hur DY, Urm SH. Am J Rhinol Allergy. 2012 May;26(3):183-6.
- Ligation of CM1 enhances apoptosis of lung cancer cells through different mechanisms in conformity with EGFR mutation. Lee HK, Park GB, Kim YS, Song H, Broaddus VC, Hur DY. Int J Oncol. 2013 Feb;42(2):469-77. doi: 10.3892/ijo.2012.1731. Epub 2012 Dec 7.
- Methotrexate induces apoptosis in nasal polyps via caspase cascades and both mitochondria-mediated and p38 mitogen-activated protein kinases/Jun N-terminal kinase pathways. Cho HW, Park SK, Heo KW, Hur DY. Am J Rhinol Allergy. 2013 Jan;27(1):e26-31. doi: 10.2500/ajra.2013.27.3849
- Bortezomib enhances antigen-specific cytotoxic T cell responses against immune-resistant cancer cells generated by STAT3-ablated dendritic cells. Kim JE, Jin DH, Lee WJ, Hur D, Wu TC, Kim D. Pharmacol Res. 2013 Feb 18;71C:23-33.
- ROS and ERK1/2-mediated caspase-9 activation increases XAF1 expression in dexamethasone-induced apoptosis of EBV-transformed B cells. Park GB, Choi Y, Kim YS, Lee HK, Kim D, Hur DY. Int J Oncol. 2013 Jul;43(1):29-38.
- The combination of DHEA, histamine, and insulin increases adipogenic differentiation and enhances tissue transplantation outcome in mice. Park Y, Jung MK, Yoon SY, Lee HR, Hur DY, Kim D, Yang Y, Kim TS, Kim S, Yoon SR, Park HJ, Bang SI, Cho DH. Biotechnol Appl Biochem. 2013 May;60(3):356-64.
- CD80 (B7.1) and CD86 (B7.2) induce EBV-transformed B cell apoptosis through the Fas/FasL pathway. Park GB, Kim YS, Lee HK, Cho DH, Kim D, Hur DY. Int J Oncol. 2013 Nov;43(5):1531-40.
- Melphalan-induced apoptosis of EBV-transformed B cells through upregulation of TAp73 and XAF1 and nuclear import of XPA. Park GB, Kim YS, Kim D, Kim S, Lee HK, Cho DH, Lee WJ, Hur DY. J Immunol. 2013 Dec 15;191(12):6281-91.
- ROS-mediated JNK/p38-MAPK activation regulates Bax translocation in Sorafenib-induced apoptosis of EBV-transformed B cells. Park GB, Choi Y, Kim YS, Lee HK, Kim D, Hur DY. Int J Oncol. 2014 Mar;44(3):977-85.
- Nasal polyp chitinolytic activity associated with smoking or allergy. Heo KW, Kim TY, Park SK, Park GB, Hur DY, Bae WY. Int Forum Allergy Rhinol. 2014 Jan 15.
- The Epstein-Barr virus causes epithelial-mesenchymal transition in human corneal epithelial cells via Syk/src and Akt/Erk signaling pathways. Park GB, Kim D, Kim YS, Kim S, Lee HK, Yang JW, Hur DY. Invest Ophthalmol Vis Sci. 2014 Mar 20;55(3):1770-9.
- Paclitaxel-exposed ovarian cancer cells induce cancer‑specific CD4+ T cells after doxorubicin exposure through regulation of MyD88 expression. Kim JE, Jang MJ, Jin DH, Chung YH, Choi BS, Park GB, Kim YS, Kim S, Hur DY, Hung CF, Kim D. Int J Oncol. 2014 May;44(5):1716-26.
- Sequential treatment of HPV E6 and E7-expressing TC-1 cells with bortezomib and celecoxib promotes apoptosis through p-p38 MAPK-mediated downregulation of cyclin D1 and CDK2. Kim JE, Lee JI, Jin DH, Lee WJ, Park GB, Kim S, Kim YS, Wu TC, Hur DY, Kim D. Oncol Rep. 2014 May;31(5):2429-37.
- Antibody ligation of CM1 on cisplatin-exposed HeLa cells induces apoptosis through reactive oxygen species-dependent Fas ligand expression. Park GB, Kim D, Yoon HS, Kim YS, Lee HK, Kim KT, Jeong DH, Hur DY. Int J Oncol. 2014 Jun;44(6):2016-24.
- Silencing of PKCη induces cycle arrest of EBV(+) B lymphoma cells by upregulating expression of p38-MAPK/TAp73/GADD45α and increases susceptibility to chemotherapeutic agents. Park GB, Choi Y, Kim YS, Lee HK, Kim D, Hur DY. Cancer Lett. 2014 Aug 1;350(1-2):5-14.
- Corticotropin-releasing factor induces immune escape of cervical cancer cells by downregulation of NKG2D. Song H, Park H, Park G, Kim YS, Lee HK, Jin DH, Kang HS, Cho DH, Hur D. Oncol Rep. 2014 Jul;32(1):425-30.
- Ligation of CD47 Induces G1 Arrest in EBV-transformed B Cells Through ROS Generation, p38 MAPK/JNK Activation, and Tap73 Upregulation. Park GB, Bang SR, Lee HK, Kim D, Kim S, Kim JK, Kim YS, Hur DY. J Immunother. 2014 Jul-Aug;37(6):309-20.
- Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation. Lee TH, Nam JG, Lee HM, Kim BY, Kang MK, Bae WY, Hur DY, Park SK. Clin Exp Otorhinolaryngol. 2014 Jun;7(2):112-8.
- MiR-9 regulates the post-transcriptional level of VEGF165a by targeting SRPK-1 in ARPE-19 cells. Yoon C, Kim D, Kim S, Park GB, Hur DY, Yang JW, Park SG, Kim YS. Graefes Arch Clin Exp Ophthalmol. 2014 Sep;252(9):1369-76.
- Silencing of galectin-3 represses osteosarcoma cell migration and invasion through inhibition of FAK/Src/Lyn activation and β-catenin expression and increases susceptibility to chemotherapeutic agents. Park GB, Kim DJ, Kim YS, Lee HK, Kim CW, Hur DY. Int J Oncol. 2015 Jan;46(1):185-94.
- ERDR1 enhances human NK cell cytotoxicity through an actin-regulated degranulation-dependent pathway. Lee HR, Huh SY, Hur DY, Jeong H, Kim TS, Kim SY, Park SB, Yang Y, Bang SI, Park H, Cho D. Cell Immunol. 2014 Nov-Dec;292(1-2):78-84.
- Hair-growth stimulation by conditioned medium from vitamin D3-activated preadipocytes in C57BL/6 mice. Jung MK, Ha S, Huh SY, Park SB, Kim S, Yang Y, Kim D, Hur DY, Jeong H, Bang SI, Park H, Cho D. Life Sci. 2015 May 1;128:39-46.
- TLR3/TRIF signalling pathway regulates IL-32 and IFN-β secretion through activation of RIP-1 and TRAF in the human cornea. Park GB, Hur DY, Kim YS, Lee HK, Yang JW, Kim D. J Cell Mol Med. 2015 May;19(5):1042-54.
- Combining CAL-101 with Celecoxib Enhances Apoptosis of EBV-transformed B-Cells Through MAPK-induced ER Stress. Park GB, Hur DY, Kim D. Anticancer Res. 2015 May;35(5):2699-708.
- Delivery of miR-155 to retinal pigment epithelial cells mediated by Burkitt’s lymphoma exosomes. Yoon C, Kim J, Park G, Kim S, Kim D, Hur DY, Kim B, Kim YS. Tumour Biol. 2016 Jan;37(1):313-21.
- Regulation of ADAM10 and ADAM17 by Sorafenib Inhibits Epithelial-to-Mesenchymal Transition in Epstein-Barr Virus-Infected Retinal Pigment Epithelial Cells. Park GB, Kim D, Kim YS, Kim JW, Sun H, Roh KH, Yang JW, Hur DY. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5162-73.
- Expression profile of ADAM10 and ADAM17 in allergic rhinitis. Chueh HW, Park SK, Hur DY, Bae WY. Int Forum Allergy Rhinol. 2015 Nov;5(11):1036-41.
- Transforming growth factor-β1 regulates human renal proximal tubular epithelial cell susceptibility to natural killer cells via modulation of the NKG2D ligands. Song H, Kim Y, Park G, Kim YS, Kim S, Lee HK, Chung WY, Park SJ, Han SY, Cho D, Hur D. Int J Mol Med. 2015 Oct;36(4):1180-8.
- Pre-stimulation of CD81 expression by resting B cells increases proliferation following EBV infection, but the overexpression of CD81 induces the apoptosis of EBV-transformed B cells. Park GB, Kim D, Park SJ, Lee HK, Kim JH, Kim YS, Park SG, Choi IH, Yoon SH, Lee YJ, Paeng S, Hur DY. Int J Mol Med. 2015 Dec;36(6):1464-78.
- ASK1/JNK-mediated TAp63 activation controls the cell survival signal of baicalein-treated EBV-transformed B cells. Park GB, Kim YS, Lee HK, Yang JW, Kim D, Hur DY. Mol Cell Biochem. 2016 Jan;412(1-2):247-58.
- Expression of ADAM17 and ADAM10 in nasal polyps. Bae WY, Park SK, Kim do H, Koh TK, Hur DY, Chueh HW. Int Forum Allergy Rhinol. 2016 Jul;6(7):731-6.
- Effects of Memantine on Aminoglycoside-Induced Apoptosis of Spiral Ganglion Cells in Guinea Pigs. Kim BY, Bae WY, Hur DY, Kim JR, Koh TK, Lee TH, Park GB. Otolaryngol Head Neck Surg. 2016 Jul;155(1):147-54.
- Berberine induces mitochondrial apoptosis of EBV-transformed B cells through p53-mediated regulation of XAF1 and GADD45α. Park GB, Park SH, Kim D, Kim YS, Yoon SH, Hur DY. Int J Oncol. 2016 Jul;49(1):411-21.
- Foxp3 is a key downstream regulator of p53-mediated cellular senescence. Kim JE, Shin JS, Moon JH, Hong SW, Jung DJ, Kim JH, Hwang IY, Shin YJ, Gong EY, Lee DH, Kim SM, Lee EY, Kim YS, Kim D, Hur D, Kim TW, Kim KP, Jin DH, Lee WJ. Oncogene. 2017 Jan 12;36(2):219-230.
- Combined treatment with vitamin C and sulindac synergistically induces p53- and ROS-dependent apoptosis in human colon cancer cells. Gong EY, Shin YJ, Hwang IY, Kim JH, Kim SM, Moon JH, Shin JS, Lee DH, Hur DY, Jin DH, Hong SW, Lee WK, Lee WJ. Toxicol Lett. 2016 Sep 6;258:126-33.
- Interleukin-32α induces migration of human melanoma cells through downregulation of E-cadherin. Lee J, Kim KE, Cheon S, Song JH, Houh Y, Kim TS, Gil M, Lee KJ, Kim S, Kim D, Hur DY, Yang Y, Bang SI, Park HJ, Cho D. Oncotarget. 2016 Oct 4;7(40):65825-65836.
- Therapeutic effect of erythroid differentiation regulator 1 (Erdr1) on collagen-induced arthritis in DBA/1J mouse. Kim KE, Kim S, Park S, Houh Y, Yang Y, Park SB, Kim S, Kim D, Hur DY, Kim S, Park HJ, Bang SI, Cho D. Oncotarget. 2016 Nov 22;7(47):76354-76361.
- Combination treatment with erlotinib and ampelopsin overcomes erlotinib resistance in NSCLC cells via the Nox2-ROS-Bim pathway. Hong SW, Park NS, Noh MH, Shim JA, Ahn BN, Kim YS, Kim D, Lee HK, Hur DY. Lung Cancer. 2017 Apr;106:115-124.
- Vandetanib and ADAM inhibitors synergistically attenuate the pathological migration of EBV-infected retinal pigment epithelial cells by regulating the VEGF-mediated MAPK pathway. Kim D, Ko HS, Park GB, Hur DY, Kim YS, Yang JW. Exp Ther Med. 2017 Apr;13(4):1415-1425.
- Methotrexate Induces Apoptosis in Organ-Cultured Nasal Polyps Via the Fas Pathway. Heo KW, Park SK, Lee YM, Choe SH, Gu PM, Hong TU, Hur DY. J Craniofac Surg. 2017 May;28(3):806-809.
- RPS27a enhances EBV-encoded LMP1-mediated proliferation and invasion by stabilizing of LMP1. Hong SW, Kim SM, Jin DH, Kim YS, Hur DY. Biochem Biophys Res Commun. 2017 Jul 20. pii: S0006-291X(17)31456-0.
- The Effects of Artemisinin on the Cytolytic Activity of Natural Killer (NK) Cells. Houh YK, Kim KE, Park S, Hur DY, Kim S, Kim D, Bang SI, Yang Y, Park HJ, Cho D. Int J Mol Sci. 2017 Jul 24;18(7).
- Epstein-Barr virus-encoded latent membrane protein 1 induces epithelial to mesenchymal transition by inducing V-set Ig domain containing 4 (VSIG4) expression via NF-kB in renal tubular epithelial HK-2 cells. Kim SM, Oh SW, Park SH, Hur DY, Hong SW, Han SY. Biochem Biophys Res Commun. 2017 Oct 21;492(3):316-322
- EBV-encoded EBNA1 regulates cell viability by modulating miR34a-NOX2-ROS signaling in gastric cancer cells. Kim SM, Hur DY, Hong SW, Kim JH. Biochem Biophys Res Commun. 2017 Dec 16;494(3-4):550-555.
- Cyclooxygenase-2 expression is induced by celecoxib treatment in lung cancer cells and is transferred to neighbor cells via exosomes. Kim J, Hong SW, Kim S, Kim D, Hur DY, Jin DH, Kim B, Kim YS. Int J Oncol. 2018 Feb;52(2):613-620.
- Novel Application of Radotinib for the Treatment of Solid Tumors via Natural Killer Cell Activation. Kim KE, Park S, Cheon S, Kim DY, Cho DJ, Park JM, Hur DY, Park HJ, Cho D. J Immunol Res. 2018 Dec 31;2018:9580561. doi: 10.1155/2018/9580561. eCollection 2018.
- High Glucose with Insulin Induces Cell Cycle Progression and Activation of Oncogenic Signaling of Bladder Epithelial Cells Cotreated with Metformin and Pioglitazone. Kim D, Ahn BN, Kim Y, Hur DY, Yang JW, Park GB, Jang JE, Lee EJ, Kwon MJ, Kim TN, Kim MK, Park JH, Rhee BD, Lee SH. J Diabetes Res. 2019 Jan 9;2019:2376512. doi: 10.1155/2019/2376512. eCollection 2019.
- LMP1 and 2A Induce the Expression of Nrf2 Through Akt Signaling Pathway in Epstein-Barr Virus-Transformed B Cells. Yun SM, Kim YS, Hur DY. Transl Oncol. 2019 May;12(5):775-783.
- Ampelopsin Induces DR5-Mediated Apoptotic Cell Death in EBV-Infected Cells through the p38 Pathway. Yun SM, Kim YS, Kim KH, Hur DY. Nutr Cancer. 2019 Jul 15:1-6.
- APX-115A, a pan-NADPH Oxidase Inhibitor, Induces Caspase-dependent Cell Death by Suppressing NOX4-ROS Signaling in EBV-infected Retinal Epithelial Cells. Hong SW, Noh MH, Kim YS, Jin DH, Moon SH, Yang JW, Hur DY. Curr Eye Res. 2020 Sep;45(9):1136-1143.
- Celecoxib upregulates ULBP-1 expression in lung cancer cells via the JNK/PI3K signaling pathway and increases susceptibility to natural killer cell cytotoxicity. Kim J, Noh MH, Hur DY, Kim B, Kim YS, Lee HK. Oncol Lett. 2020 Dec;20(6):279.
- VSIG4 Induces Epithelial-Mesenchymal Transition of Renal Tubular Cells under High-Glucose Conditions. Gong EY, Jo HA, Park SH, Cha DR, Hur DY, Han SY. Life (Basel). 2020 Dec 17;10(12):354.
- Erlotinib Activates Different Cell Death Pathways in EGFR-mutant Lung Cancer Cells Grown in 3D Versus 2D Culture Systems. Lee HK, Noh MH, Hong SW, Kim SM, Kim SH, Kim YS, Broaddus VC, Hur DY. Anticancer Res. 2021 Mar;41(3):1261-1269.
- Effects of Epstein-Barr Virus Infection on the Response of Human Breast Cancer Cells to Nicotine. Rajbongshi L, Noh MH, Kim YS, Hur DY. Anticancer Res. 2021 Jul;41(7):3449-3458.
- Olaparib-induced Apoptosis Through EBNA1-ATR-p38 MAPK Signaling Pathway in Epstein-Barr Virus-positive Gastric Cancer Cells. Moon SH, Park NS, Noh MH, Kim YS, Cheong SH, Hur DY. Anticancer Res. 2022 Jan;42(1):555-563. doi: 10.21873/anticanres.15513.
- Morphologic Changes in Esophageal Body Movement During Bolus Transport After Peroral Endoscopic Myotomy in Type III Achalasia. Kim AJS, Ong S, Kim JH, Lee HS, Yoon JS, Hur DY. J Neurogastroenterol Motil. 2022 Jan 30;28(1):131-144. doi: 10.5056/jnm21020.
- Upregulation of VSIG4 in Type 2 Diabetic Kidney Disease. Han SY, Ghee JY, Cha JJ, Kang YS, Hur DY, Kim HS, Cha DR. Life (Basel). 2022 Jul 11;12(7):1031. doi: 10.3390/life12071031.
- 15-Prostaglandin Dehydrogenase Inhibition Enhances Colon Cancer Metastasis by Up-regulation of Epithelial-to-Mesenchymal Transition Genes. Kim SH, Song SE, Baik H, Hur DY, Kang MS, Bae KB. Anticancer Res. 2022 Nov;42(11):5385-5396. doi: 10.21873/anticanres.16043.
- Pan-Aurora Kinase Inhibitor Danusertib Induces Apoptosis of Epstein-Barr Virus-transformed B-Cells Through Caspase and Endoplasmic Reticulum Stress Signaling. Kim JS, Hur DY. Anticancer Res. 2022 Nov;42(11):5265-5274. doi: 10.21873/anticanres.16033.
- The Role of V-Set Ig Domain-Containing 4 in Chronic Kidney Disease Models. Han SY, Ghee JY, Cha JJ, Kang YS, Kim HS, Hur DY, Cha DR. Life (Basel). 2023 Jan 19;13(2):277. doi: 10.3390/life13020277.